As published in
The New York Times
July 18, 2002

To the Editor:
What has been tested and found risky is one particular drug, Prempro, a pharmaceutical that combines conjugated estrogen with a synthetic progestin.

Unfortunately, the study made no provision to follow the risks to women of supplemental estrogen in combination with natural progesterone on an intermittent cyclic basis, a regimen least likely to increase risks of breast cancer, heart attacks, and strokes.

Women should not be left thinking that all estrogen-progestin hormone replacement therapy is hazardous. What a pity that the study was poorly designed and that its conclusions lend themselves so well to misinterpretation.

Susan Rako, M.D.
Newtonville, Mass.,

INDIVIDUAL CONSULTATIONS

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